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These analyses revealed that the individual was closely related to Native Americans in Central and South America, instead of being closely related to the people of the Canadian Arctic, as had previously been thought likely.(The people of the Arctic are distinct from Native Americans to the south, including in lower North America and Central and South America.) The infant was also related to persons from Siberia and Central Asia, believed to be the ancestral population of indigenous peoples in the Americas.The Anzick-1 paleogenetic analysis lends support to the Beringia Hypothesis theory, showing that humans had arrived in Montana by nearly 13,000 years ago.Some mt DNA evidence supports this hypothesis because haplogroup X, found in some Native American communities in northeastern North America, originated in Europe where the Solultrean culture developed.These bones were discovered in highly fragmented states; however, partial reconstruction of the crania allowed for age estimation, investigation of basic health indicators, and some information about cultural practices.Originally, investigators thought the left clavicle showed evidence of cremation, but further analysis revealed that the discoloration was the result of groundwater staining and not fire.Another concept is that they used boats to sail along the coast of Siberia, the Beringia land bridge, and the Pacific coast of North America.

For more than 20 years, some anthropologists have debated whether the first settlers who came to the New World did so by crossing a land bridge through the Bering Strait, or by sea from the southwest of Europe, in what is called the Solutrean Hypothesis.

Anzick-1's discovery and subsequent analysis has been controversial.

The remains were found on private land, so the researchers did not violate the Native American Graves Protection and Repatriation Act (NAGPRA) in their study.

Like mt DNA, these mutations can be grouped and categorized into haplogroups.

The y-chromosome of Anzick-1 was sequenced, and researchers determined that his y-chromosome haplogroup is Q-L54*(x M3), one of the major founding lineages of the Americas.

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